2025 CSBC Annual Meeting

This event will take place in the Marlo Thomas Center Meeting Room 3 (IA1406).

See the details JI Pre-Event Meeting Agenda here.

8:30 AM - Shuttle from Hotel Indigo to Campus

9:00 - 9:30 AM   Arrival + intro + coffee and pastries, provided by the MC² Center    

9:30 - 10:00 AM  Talks

10:00 - 10:30 AM   Talks

10:30 - 11:00 AM   Discussion/Break

11:00 - 11:30 AM  Talks

11:30 AM - 12:00 PM   Talks

12:00 - 12:30 PM   Talks

12:30 - 1:15 PM   Lunch    

1:15 - 2:00 PM   Collaboration "Speed Dating"    

2:00 - 3:00 PM   ITCR 

3:00 - 3:10 PM   Break    

3:10 - 4:00 PM   PI career panel     

4:00 - 4:10 PM   Conclusion    

4:15 PM    Shuttle back to the hotel   

Appetizers provided by the MC² Center. Drinks will be available for purchase.

Shuttles depart at 7:45 and 8:15 AM. 

We ask that all speakers for the day board the 7:45 shuttle.

Coffee provided by the MC2 Center / Sage Bionetworks

 Tech check for all Day 1 Speakers

Amy Brock (University of Texas at Austin) and David Basanta Gutierrez (Moffitt Cancer Center)

Jiyang Yu, St. Jude Children's Research Hospital

Session Chairs: Junmin Peng and Jiyuan Yang, St. Jude Children's Research Hospital

9:30 - 9:45 AM    Trey Ideker (UCSD), The Cancer Cell Map Initiative: 2025 Update

9:45 - 10:00 AM    Yogesh Dhungana (St. Jude), scMINER2 - A causal feature learning framework to untangle cell-type-resolved hidden gene regulatory network (hGRN)

10:00 - 10:15 AM    Rachel Karchin (Johns Hopkins University), Clone-Specific Pathway and Program Inference in Low- to High-Grade IPMN Precursors of Pancreatic Cancer

10:15 - 10:30 AM    Alev Baysoy (Yale), Perturb-DBiT for Spatially Resolved, Whole-Transcriptome In Vivo CRISPR Screens

All poster presenters please attach their posters.

Session Moderators: Pamela Jackson, Cedars Sinai, and Chandler Gattenbee, Moffitt 

11:00 - 11:15 AM    Matthew Lazzara (UVA), Regulation of macropinocytosis in cancer cell settings with elevated Ras activity

11:15 - 11:30 AM    Forest White (MIT), Identification of immunotherapeutic targets in the GBM:immune microenvironment   

11:30 - 11:45 AM    Diana Murray (Columbia), A proteome-wide structurally resolved protein interactome for an atomistic perspective of cancer signaling

11:45 - 12:00 PM    Kristin Swanson(Cedars-Sinai), Characterizing the metabolic landscape of high-grade glioma with respect to transcriptional subtype and imaging region

Lunch is provided by the MC² Center / Sage Bionetworks

 If you have not attached your posters, please do so now

Led by Todd Stukenberg, University of Virginia, on behalf of the Education & Outreach Working Group

In Marlo Thomas Meeting Room 5 (IA1503)

Led by Andrea Califano, Columbia University

In Chili's Care Center CRI6101

Dr. Charles W.M. Roberts, MD, PhD

Executive Vice President

Director, Comprehensive Cancer Center

St. Jude Children's Research Hospital

Introduced and moderated by: Jiyang Yu, St. Jude Children's Research Hospital

Session Moderator: Amy Brock, UT Austin, and David Basanta Gutierrez, Moffitt

In this session we will start in the auditorium and then be sent to your breakout rooms. Breakout rooms will be by assignment. View your room assignments here.

Find the collated Critical Unmet Slides here and the Notes Document here.

Session Chair: Todd Stukenberg, UVA

1) Michael Cotner

2) Alvaro Curiel Garcia

3) Yogesh Dhungana

5) Dina Hany

6) Yukiko Higa

7) Kennedy Howland

9) Ilayda Ilerten

12) Kimya Karimi

13) Marcus Kelly

15) Minjeong Kim

16) Jiaying Lai

17) William Leineweber

18) Sarah Meng

19) Naveed Pervaiz

20) Daniel Phipps

21) Sandhya Prabhakaran

22) Aakash Saha

24) William Shao

26) Austyn Smithback

28) Ruohan Wang

29) Chong Xia

30) Zhen Xie

31) Jiyuan Yang

Appetizers provided by Sage Bionetworks

Odd Numbered Posters: 4:00 - 4:45 PM

Even Numbered Posters: 4:45 - 5:30 PM 

in ARC Lobby

We'll host you at Silky O’Sullivans on the corner of Beale St &, 183 Beale Street, S B.B. King Blvd, Memphis, TN 38103) The social includes a hosted dinner, plus access to live music. The menu will accommodate common dietary restrictions, including vegetarian, vegan and gluten free.

Shuttles are not provided to the dinner. We encourage you to take Uber/Lyft or Taxi.

Shuttles depart at 7:45 and 8:15 AM. 

We ask that all speakers for the day board the 7:45 shuttle.

Coffee provided by the MC2 Center / Sage Bionetworks

 Tech check for all Day 2 Speakers

Session Moderators: Linghua Wang, MD Anderson, and Marcus Kelly, UCSD

9:00 - 9:15 AM    Humam Kadara (MD Anderson), Co-evolution of tumor progenitors and their microenvironment in progression of lung premalignancy to adenocarcinoma

9:15 - 9:30  AM    José Reyes (Memorial Sloan Kettering), Oncogenic and tumor-suppressive forces converge on a progenitor-orchestrated niche to shape early tumorigenesis 

9:30 - 9:45 AM    Brendan Ball (Stanford), Mouse lymph node colonization models predict human tumor metastasis in melanoma

9:45 - 10:00 AM    Aritro Nath (City of Hope), ErbB Pathway Activation and SMARCD3 Regulons Drive Resistance in ER+ Breast Cancer

St. Jude Campus Tours will start outside of the Marlo Thomas Auditorium and end outside of the Marlo Thomas Center. Tours will be staggered. 

View your tour assignments here.

Session Moderators: Kevin Janes, UVA, Minjeong Kim, University of Tennessee Health Science Center

11:30 - 11:45 AM    Alexander Anderson (Moffitt), Phase i trials in cancer: From board to bench to bedside and back again

11:45 - 12:00 PM    Pamela Jackson (Cedars-Sinai), Leveraging AI for Brain Tumor Resection: Predicting 5-ALA Fluorescence on Preoperative MRI

12:00 - 12:15 PM  Tatiana Miti (Moffitt), Mathematical Modeling of JNK Pathway Dynamics to Optimize Therapeutic Strategies for Triple-Negative Breast Cancer Lung Metastasis

12:15 - 12:30  PM    Andrea Califano (Chan Zuckerberg Biohub), Quantum Cancer Biology: Systematic Elucidation and pharmacologic targeting of Master Regulator dependencies presiding over coexisting pancreatic cancer subpopulations, at the single cell level

Lunch is provided by the MC2 Center / Sage Bionetworks

Chair: Jiyang Yu, St. Jude Children's Research Hospital

Angelique C. Graham Harlan, Patient Advocate (ALSAC) - Face Behind the Findings

Franziska Michor (Dana-Farber Cancer Institute), Systems Biology Approaches to Pediatric Oncology

Wesley Tansey (MSKCC), Characterizing the spatial architecture of SMARCB1-deficient epithelioid sarcomas with Modulator

Darryl Shibata (USC), Conception-calibrated pediatric tumor mitotic clocks

Jiyang Yu (St. Jude Children's Research Hospital), A hidden-driver framework reveals synergistic brain-penetrant therapies for medulloblastoma 

Session Moderator: Amy Brock, UT Austin

In this session we will start in the auditorium and then be sent to your breakout rooms. Breakout rooms will be by assignment. View your room assignments here.

Chair: Amy Brock, UT Austin

Session Chair: Jiyuan Yang, St. Jude Children's Research Hospital

3:30pm - 3:45pm: Massively parallel in situ generation and evaluation of cancer coding variants - Marcus Kelly, UCSD

3:45pm - 4:00pm: PrePPI: Proteome-wide Prediction of Protein-Protein Interactions via Domains and Peptides - Aakash Saha, Columbia University

4:00pm - 4:15pm: SubCell: Proteome-aware vision foundation models for single-cell biology - Will Leinweber, Stanford University

4:15pm - 4:30pm: Systems Genetics and Integrative Genomics Reveal Human-like Breast Cancer Profiles from Breast Cancer Murine Model - Jay Kim, UT Health Science Center

Anyone still around is welcome to join